In this study, 5d after operation, the RBC, PLT, HCT, and Hb of the allogeneic group were lower than those before operation, and the autologous group was higher than that of the allogeneic group ( 0

In this study, 5d after operation, the RBC, PLT, HCT, and Hb of the allogeneic group were lower than those before operation, and the autologous group was higher than that of the allogeneic group ( 0.05). cells (RBC), platelets (PLT), hematocrit (HCT), hemoglobin (Hb)], T-cell subsets (CD4+, CD8+, CD4+/CD8+), immunoglobulins (IgA, IgM, IgG), inflammatory factors [C-reactive protein (CRP), tumor necrosis factor (TNF)-, interleukin (IL)-6], and adverse effects were counted in both groups. Results There was no statistical significance in the intra-group and inter-group comparisons of HR, MAP, and SVV between the two groups before transfusion and transfusion for 10 min ( 0.05). 5d after operation, the RBC, PLT, HCT, and Hb of the allogeneic group were lower than those before operation, and the autologous group was higher than that of the allogeneic group ( 0.05). 5d after operation, the CRP, TNF-, and IL-6 of the allogeneic group were higher than those before operation, and the autologous group was lower than that of the allogeneic group ( 0.05). 5d after Mouse monoclonal to CD29.4As216 reacts with 130 kDa integrin b1, which has a broad tissue distribution. It is expressed on lympnocytes, monocytes and weakly on granulovytes, but not on erythrocytes. On T cells, CD29 is more highly expressed on memory cells than naive cells. Integrin chain b asociated with integrin a subunits 1-6 ( CD49a-f) to form CD49/CD29 heterodimers that are involved in cell-cell and cell-matrix adhesion.It has been reported that CD29 is a critical molecule for embryogenesis and development. It also essential to the differentiation of hematopoietic stem cells and associated with tumor progression and metastasis.This clone is cross reactive with non-human primate operation, the CD4+, CD4+/CD8+ of the allogeneic group were lower than before operation, and the CD8+ was higher than before operation. The CD4+ and CD4+/CD8+ of the autologous group were higher than that of the allogeneic group, and CD8+ was lower than that of the allogeneic group ( 0.05). 5d after operation, the IgA, IgG, and IgM of the allogeneic group were lower than SYP-5 those before operation, and the autologous group was higher than that of the allogeneic group ( 0.05). During blood transfusion, there was no significant difference in the adverse reaction rate between the two groups ( 0.05). Conclusion Both allogeneic transfusion and ANH autologous transfusion have little effect on the vital signs of patients undergoing cesarean section, but ANH autologous transfusion is more helpful to the stability of blood routine, T-cell subsets, immunoglobulin, and inflammation levels after surgery, SYP-5 which is a safe and effective way of blood transfusion. = 55) receiving allogeneic transfusion therapy and the autologous group (= 55) receiving ANH autologous transfusion therapy according to the mode of blood transfusion. There was no significant difference between the two groups in terms of age, gestational weeks and other general conditions, which were comparable, which were comparable ( 0.05) (Table 1). Table 1 Comparison of patients’ general conditions ( = 55) = 55) value the internal jugular vein. autologous blood was transfused at the end of the main intraoperative step or when the bleeding volume was 1, 000 mL or Hb was 100 g/L. Observation Index (1) Vital signs: heart rate (HR), mean arterial pressure (MAP), and stroke volume variation (SVV) were monitored before transfusion and transfusion for 10 min by a PICCO monitor (purchased from Beijing Shimao Medical Equipment Trading Co., Ltd.). (2) Blood routine: The red blood cell (RBC), PLT, HCT and Hb levels were measured before and 5 d after surgery by MAXM automatic hematology analyzer (purchased from Beckman Coulter, Inc.). (3) T-cell subsets: The CD4+, CD8+, CD4+/CD8+ levels were measured before and 5 d after surgery by a Cytomics FC500 flow cytometer (purchased from Beckman Coulter, Inc.). (4) Immunoglobulins: The IgA, IgM, and IgG levels were measured before and 5 d after surgery by enzyme-linked immunosorbent assay (The kit was purchased from Roche). (5) Inflammatory factors: C-reactive protein (CRP), tumor necrosis factor (TNF)- and interleukin (IL)-6 levels were measured before and 5 d after surgery by enzyme-linked immunosorbent assay (The kit was purchased from Shanghai Sange Biotechnology Co., Ltd.). (6) Adverse reaction rate: Allergy, fever, hemolysis and other adverse reactions occurred during blood transfusion in the two groups were counted. Statistical Methods SPSS 22.0 software was applied, and the measurement data were expressed as mean standard deviation ( 0.05 was considered statistically significant. Results Effect of Different Blood Transfusion Methods on Patients’ Vital Signs There was no statistical significance in the intra-group and inter-group comparisons of HR, MAP, and SVV between the two groups before transfusion and transfusion for 10 min ( 0.05) (Figure 1). Open in a separate window Figure 1 Effect of different blood transfusion methods on patients’ vital signs. (A) HR, (B) SYP-5 MAP, and (C) SVV. Effect of Different Blood Transfusion Methods on Patients’.